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Assisted Hatching

WHAT IS ASSISTED HATCHING?

  • Assisted hatching is an additional microscopic laboratory procedure designed to increase the chances of pregnancy ,performed in patients who are undergoing in vitro fertilization (IVF) treatment to facilitate embryo hatching and implantation process.
  • Once embryos are created using IVF, the embryo is surrounded by a hard outer layer of cells called the zona pellucida. You can think of this outer layer as the “shell” of the embryo.
  • To result in a successful pregnancy, embryo must break free of this “shell”(zona pellucida) in order to implant into the uterus . Assisted hatching is a procedure where we can help the embryo “hatch” from its “shell” by creating a small crack in the zona pellucida. It is believed that assisted hatching can help an embryo implant in the uterus, leading to higher pregnancy rates in some patients.

 HOW ASSISTED HATCHING IS DONE?

  • During assisted hatching, the outer shell of the embryo is artificially weakened by making a small hole in the zona pellucida. This can be done in several different ways like mechanical expansion of shell, chemical hatching, drilling, laser assisted hatching
  • Laser assisted hatching is a more modern approach which is the safest and most effective. It utilizes specialized software that aids in the positioning, intensity, and focus of the lasers.

 WHO ARE IDEAL FOR THE PROCEDURE?

  • Assisted hatching is not recommended for all patients, but may be helpful in women who are older (more than 37 years old) or who have had at least two IVF failures.
  • Patients who have poor quality embryo, patients whose embryos have a zona pellucida that is unusually thick, patients whose embryos are not developing as well as expected, patients with elevated FSH levels during the follicular phase.
  • Assisted hatching can also be done on previously frozen and thawed embryos as freezing can make it harder for embryos to hatch.
  • If the preimplantation genetic diagnosis (PGD) is planned, assisted hatching of embryos on the third day after fertilization can make a biopsy for PGD easier.

 RISK ASSOCIATED WITH ASSISTED HATCHING

  • There is a slightly increased risk for identical twins in embryos that have undergone assisted hatching. Very rarely, an embryo can be damaged from the assisted hatching process.

FAQ's

What is laser assisted hatching in IVF?

Laser-assisted hatching is a technique used during IVF where a laser is used to create a small opening in the outer shell (zona pellucida) of the embryo to help it hatch and implant in the uterus. At Felicity IVF and Fertility Center, we offer laser-assisted hatching as part of our advanced fertility treatments, providing personalized care and support to maximize your chances of successful conception.

What is the success rate of assisted hatching?

The success rate of assisted hatching varies depending on individual factors such as age and reproductive health. However, it has been shown to improve implantation rates, particularly in certain cases such as advanced maternal age or previous IVF failures. At Felicity IVF and Fertility Center, we provide personalized assessments and support to optimize your chances of success with assisted hatching, guiding you through your fertility journey with care and expertise.

What are the risks of assisted hatching?

Assisted hatching is generally safe but may carry some risks, including damage to the embryo or increased risk of multiples. However, these risks are minimal when performed by experienced professionals. At Felicity IVF and Fertility Center, we prioritize your safety and well-being, providing thorough assessments and personalized care to minimize any potential risks associated with assisted hatching and ensure the best possible outcome for you.

Does assisted hatching increase chances of twins?

Assisted hatching may slightly increase the chances of twins or multiples, although the overall risk remains low. At Felicity IVF and Fertility Center, we provide personalized assessments and support to optimize your chances of successful conception with assisted hatching, ensuring that any potential risks, including the possibility of twins, are carefully considered and discussed with you.

How long does it take an assisted hatched embryo to implant?

After assisted hatching, an embryo typically implants in the uterus within 1 to 2 days. However, the exact timing may vary for each individual. At Felicity IVF and Fertility Center, we closely monitor your progress and provide support throughout the implantation process, ensuring the best possible outcome for you.

What are the methods of assisted hatching?

The methods of assisted hatching include mechanical, chemical, and laser-assisted techniques. Mechanical methods involve the use of micropipettes to create an opening in the zona pellucida, while chemical methods use acid or enzymes to weaken the shell. Laser-assisted hatching, like at Felicity IVF and Fertility Center, employs a precise laser to create an opening, offering greater control and accuracy in the process, ultimately enhancing the chances of successful implantation.

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